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CE Course Description

Neuropsychiatric symptoms (NPSs) are hallmarks of Alzheimer’s disease (AD), causing substantial distress for both people with dementia and their caregivers, and contributing to early institutionalization.  This CE course explores the neurobiology of NPSs in AD and specific symptoms common in AD such as psychosis, agitation, apathy, depression, and sleep disturbances.  In addition, clinical trial designs for NPSs in AD and regulatory considerations will be discussed.

Author:  Lanctot, K., Amatniek, J., Ancoli-Israel, S., Arnold, S., Ballard, C., Cohen-Mansfield, J., et al.  (2017, September).  Neuropsychiatric signs and symptoms of Alzheimer’s disease: New treatment paradigms.  Alzheimer’s & Dementia: Translational Research & Clinical Interventions.  Vol 3, Issue 3, Pages 440-449.  Open access.

Retrieved from:  https://www.trci.alzdem.com/

CE Course Objectives

1. Conclude which cholinesterase inhibitor has shown improvements in apathy.
2. Describe four aspects of hallucinations in AD.
3. Name the most common NPS in AD.
4. Provide the order in which the phases of NPSs emerge.

CE Outline with Main Points

1.  Introduction

2.  History and overview

3.  The neurobiology of NPSs in AD

4.  Neuropsychiatric symptoms

a.  Psychotic symptoms in AD

b.  Agitation in AD

c.  Apathy in AD

d.  Depression in AD

e.  Sleep disturbances and AD

5.  Design for NPS trials

6.  Regulatory Considerations

ACE credit is not offered for this course. A list of courses offering ACE credit can be found here.

Course Development: Each course is identified and reviewed by the appropriate Quantum Units Education consultant with professional and licensed expertise in the various disciplines we serve. Our professional consultants oversee course development to satisfy the needs of various professionals based on their board requirements, rate course degrees of difficulty and ensure the course content and exam questions are appropriate, relevant and comprehensive. See our professional staff and their bios here.

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Added On: 09/01/2017